Before you get ready to buy Xanax online, you should know that the drug is only prescribed to treat anxiety and panic disorders and is the brand name of the drug Alprazolam. Thus, if you buy the drug and take it with the help of a prescription, you should also know that the drug can cause harmful side effects when it interacts with alcohol, drugs, or other substances. To know more, let us describe the interaction of Xanax with the following:-


Use with other CNS depressants

Before you start taking the drug Xanax or Alprazolam, a thing that needs to be remembered by you is that if the tablets of the drug are taken in combination with other psychotropic agents or drugs that prevent the occurrence of seizures, then careful consideration should be given to the pharmacology of the agents to be employed, particularly with compounds which might increase the effect of the action of benzodiazepines. The drug produces addictive CNS depressant effects when combined with other CNS depressants.


Use with Digoxin

Increased concentration of digoxin, taken to treat heart failure, have been reported when it interacts with Xanax, especially when it comes to the treatment of symptoms of anxiety and panic disorders found in senior citizens. Patients who take both the drugs in combination with each other should be checked for signs and symptoms of digoxin toxicity.


Use with Imipramine and Desipramine

The steady state plasma concentrations of imipramine and desipramine, taken mainly to treat depression, have been reported to have increased to an average percentage of 31% and 20%, respectively, by the naturally occurring administration of Xanax tablets in doses up to 4mg/day. The clinical significance of these changes is unknown.


There are other medications that can affect the removal of Xanax from a person’s body, which may or may not affect the working method of the drug. The example of such medications include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), among others. In total, there are 953 medications that are known to interact with Xanax, out of which 138 are major drug interactions, 707 are moderate drug interactions, and 108 are minor drug interactions. If we go on to describe how these interactions are different from each other, then major drug interaction is highly clinically significant, moderate is moderately clinically significant, and minor is minimally clinically significant.

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